Segmental late gadolinium enhancement and gadolinium extracellular volume in hypertrophic cardiomyopathy

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Segmental late gadolinium enhancement and gadolinium extracellular volume in hypertrophic cardiomyopathy

Background Late gadolinium enhancement (LGE) by cardiac magnetic resonance (CMR) is a common finding in patients with hypertrophic cardiomyopathy (HCM), and its extent correlates with clinical parameters such as ventricular tachycardia and sudden cardiac death. While LGE has been shown to reflect focal replacement fibrosis, recently optimized T1 mapping techniques have allowed for the quantific...

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Exuberant Pattern of Late Gadolinium Enhancement in Hypertrophic Cardiomyopathy

Patient aged 42, Caucasian, asymptomatic, with family history of HCM and diagnosis of the same cardiomyopathy 22 years ago. The 24-h Holter heart rhythm monitoring (April 5, 2012) showed sinus rhythm, rare atrial ectopic beats, presence of 2,970 isolated ventricular extrasystoles and five outbreaks of non-sustained ventricular tachycardia (NSVT), the longest one presenting 13 QRS complexes. Giv...

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[What is late gadolinium enhancement in hypertrophic cardiomyopathy?].

Hypertrophic cardiomyopathy (HCM) is a condition that can be defined in three ways: genetically, as caused by sarcomeric protein mutations; phenotypically by the presence of unexplained hypertrophy in the absence of afterload; and histologically by myocardial fibrosis, disarray, and small vessel disease. All these definitions have problems: only around half of HCM cases have an identifiable mut...

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ژورنال

عنوان ژورنال: Journal of Cardiovascular Magnetic Resonance

سال: 2016

ISSN: 1532-429X

DOI: 10.1186/1532-429x-18-s1-p155